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Civatte bodies are PAS positive. Eosinophils are uncommon in conventional cutaneous lichen planus. Dyskeratotic keratinocytes (Civatte bodies) Acanthosis Junctional split seen at the junction of the epithelium and lamina propria (unlike sloughing esophagitis) Foreign bodies indicate a foreign body granuloma. Specific forms of multinucleated giant cells include the Touton giant cell, which contains a ring of nuclei surrounding a central homogeneous cytoplasm, with foamy cytoplasm surrounding the nuclei. The central cytoplasm (surrounded by the nuclei) may be both amphophilic and eosinophilic. COMMENT: The histologic sections show squamous mucosa with increased intraepithelial lymphocytes with a prominent lichenoid pattern of injury with numerous apoptotic keratinocytes (“Civatte bodies”). This pattern of injury is nonspecific and can be seen in association with gastroesophageal reflux (GERD), cutaneous lichen planus, contact mucositis, graft-versus-host disease, certain medications (including NSAIDs, among many others), viral infections, Crohn’s disease, and pill esophagitis.

Dyskeratotic keratinocytes (so called Civatte bodies) are frequently seen at the basal layer. Civatte bodies are PAS positive. Eosinophils are uncommon in conventional cutaneous lichen planus. Lichen planus may occur on mucosal surfaces such as the oral mucosa or genitalia. Civatte bodies . Wedge-shaped hypergranulosis “Saw-tooth” rete ridges . Single lesion on trunk?

2020-10-28 · Some cases will also show basal layer degeneration and the formation of Civatte bodies (Figure 1(c)), the result of a lichenoid infiltrate with irregular acanthosis. This can be distinguished from lichenoid dermatitis by the presence of keratinocyte atypia.

‘ Hyaline bodies’ are equivalent but occur in connective tissue. Eosinophilic apoptotic (necrotic) keratinocytes in the lower epidermis and at the dermoepidermal junction are a feature of many interface dermatoses but are most reliably found in lichen planus. These structures are universally known as Civatte bodies. Nonetheless, they were first described by Raymond Sabouraud in 1912.

Civatte bodies . Wedge-shaped hypergranulosis “Saw-tooth” rete ridges . Single lesion on trunk? Consider Lichen Planus-like Keratosis (LPLK) Common entity, unknown etiology; Pruritic, purple, papules

At the dermal level, and civatte bodies near the tips of rete ridges, consistent with hypertrophic lichen planus (Figure 3). He was treated with topical clobetasol ointment twice daily Close. Indian J Med Microbiol. Figure 2: (a) Photomicrograph of classic lichen planus, (H and E, ×100).
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Wedge-shaped hypergranulosis “Saw-tooth” rete ridges .

poikiloderma of Civatte - reticulated pigmentation and telangiectasia of the sides of the cheeks and neck; common in middle-aged women. Civatte Bodies: A Diagnostic Clue Introduction. The presence of numerous civatte bodies (CBs) in biopsies is a characteristic finding in skin lesions of History. CBs have been variously termed cytoid, hyaline, colloid, or keratin bodies.
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They are known as CBs (in epithelium/epidermis), colloid bodies, or hyaline bodies (in connective tissue). They are 10-25 micrometers in diameter and situated mostly within or above the inflammatory cell infiltrate.

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Foreign bodies indicate a foreign body granuloma. Specific forms of multinucleated giant cells include the Touton giant cell, which contains a ring of nuclei surrounding a central homogeneous cytoplasm, with foamy cytoplasm surrounding the nuclei. The central cytoplasm (surrounded by the nuclei) may be both amphophilic and eosinophilic.

He was treated with topical clobetasol ointment twice daily Close. Indian J Med Microbiol. Figure 2: (a) Photomicrograph of classic lichen planus, (H and E, ×100). Inset – civatte bodies, shown by arrows, (H and E, ×400) . Close. Indian J Med Microbiol. Figure 2: Histopathology showing thinned out epidermis with spongiosis and civatte bodies (H and E, ×400).

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Jun 13, 2019 This epidermal basal cell damage can be of two forms: vacuolar/hydropic degeneration and filamentous degeneration (resulting in Civatte bodies) Lupus is a chronic autoimmune condition that can cause inflammation throughout your body. However, it tends to primarily be a localized condition, so it's not Isolated, degenerated keratinocytes (Civatte, or hyaline, bodies) are present at the epithelial-stromal junction (figures 2 and 3). Erosive LP may show ulceration or Jun 12, 2018 were observed along with a focal lichenoid inflammatory cell infiltrate with colloid bodies corresponding to Civatte bodies. At the dermal level, and civatte bodies near the tips of rete ridges, consistent with hypertrophic lichen planus (Figure 3).

Simply select a language and press on the speaker button to listen to the pronunciation of the word. Leave a vote for your preferred pronunciation. Often vacuolar degeneration of basal keratinocytes and apoptotic bodies (colloid or Civatte bodies). Lichen planus Irregular epidermal hyperplasia with a jagged “sawtooth” appearance, compact hyperkeratosis or orthokeratosis, foci of wedge-shaped hypergranulosis, basilar vacuolar degeneration, slight spongiosis in the spinous layer, and squamatization.